A University of Melbourne graduate, A/Prof Sikaris trained at the Royal Melbourne, Queen Victoria, Prince Henry's and Heidelberg Repatriation Hospitals. He obtained fellowships from the Royal College of Pathologists of Australasia (RCPA) and the Australasian Association of Clinical Biochemists (AACB) in 1992 and 1997 respectively.
A/Prof Sikaris was appointed Director of Chemical Pathology at St Vincent's Hospital in 1993 and Medical Director of Dorevitch Pathology in 1998 before starting at Melbourne Pathology in 2003. He specialises in Prostate Specific Antigen, cholesterol and quality assurance and is Chair of the RCPAQAP Key Incident Monitoring Program for Australasia.
A NATA-accredited laboratory assessor, he is also founding Fellow of the RCPA Faculty of Science where he is Principal Examiner in Pathology Informatics. He currently sits on the Board of Examiners at AACB, and was past Vice President (Education) .
A/Prof Sikaris is a Principal Fellow of the Department of Pathology at Melbourne University and lectures to undergraduates, GPs and a variety of specialist groups across Australia and overseas.
A/Prof Sikaris is also Director of Clinical Support Services for Sonic Healthcare and Director of Chemical Pathology at Melbourne Pathology.